Prevalence of Multidrug Resistant Enterococci in Nosocomial Infection In Gaza Strip

الجاروشة, عبد المعطي خيري and عفيفي, أحمد محمد (2008) Prevalence of Multidrug Resistant Enterococci in Nosocomial Infection In Gaza Strip. Al-Aqsa University Journal (Natural Sciences Series), 12 (1). pp. 15-24. ISSN 2070-3155 (Print), ISSN 2521-893X (Online)

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Enterococci leading causes of nosocomial infection like bacteremia, surgical wound infection, lower respiratory tract, and urinary tract infection, these organisms are becoming resistant to many and sometimes all standard antibiotics, most enterococcal infections are caused by Enterococcus faecalis which are more likely to express traits related to over virulence. The remaining infections are mostly caused by Enterococcus faecium, a species virtually devoid of known overt pathogenic traits but more likely to be resistant to even antibiotics. 309 clinical samples included (116 Urine, 104 Pus, 67 Blood, and 22 Sputum) samples were processed to find the prevalence rate of enterococci and identify the species of clinical isolates of enterococci. Screening of various clinical specimens revealed that enterococci were prevalent in 1.9% of the total nosocomial infected cases. The most effective antibiotics were Linzolid followed by Nitrofurantoin, Chloramphenicol and Ciprofloxacin. Where Amikacin, Gentamicin, Erythromycin and Lincomycin showed moderate activities. At the same time Methicillin, Ampicillin, Tetracycline, Aztreonam, Cefuroxime and Cefotaxim showed resistance. Non of the available Cephalosporins, Monobactams, Aztreonam or semisynthetic Penicillins (Naficillin, Oxacillin) have any activity against enterococci. Vancomycin resistant strains were recorded in this study The distribution of enterococci cases showed highest rate in lower respiratory tract infection (4.5%), blood stream infection (3%), surgical wound infection (1.9%), and urinary tract infection (0.8%). Key wards: Enterococci, Nosocomial infection, Multidrug resistance

Item Type: Article
Subjects: Q Science > QR Microbiology
R Medicine > R Medicine (General)
Depositing User: أ. دارين علي أحمد حمد
Date Deposited: 14 Oct 2021 08:39
Last Modified: 31 Oct 2021 10:59

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